Preheat the oven to 350ºF (177ºC), Spray an 8½x4½" or 9x5" loaf pan with nonstick spray. Place a piece of parchment paper that’s cut to the width of the pan, lengthwise in the pan, allowing overhang. Spray the parchment paper with nonstick spray and set aside.
Whisk together flour, baking soda, baking powder, salt, and apple pie spice in a large bowl. Set aside.
Whisk granulated sugar and eggs together in a medium bowl. Mix together well for about 35 seconds.
Add apple cider, melted butter, buttermilk and vanilla extract. Mix well.
Pour the wet ingredients into the dry ingredients and gently whisk until dry ingredients are moistened.
Pour batter into prepared pan and even out with spatula.
Bake for 45-55 minutes or until a toothpick comes out clean. Baking times vary so keep an eye on yours. The cake is done when a toothpick inserted in the center comes out mostly clean with zero raw batter. Remove the pan from oven.
Cool cake in the pan and set it on a wire rack for 15 minutes before removing from the pan. Carefully remove loaf from pan. Let cool completely on wire rack.